|
KMID : 0358320070480090927
|
|
Korean Journal of Urology
2007 Volume.48 No. 9 p.927 ~ p.932
|
|
|
The Prognostic Significance of Elevated Serum Creatinine for the Recurrence and Progression in Superficial Bladder Tumors
|
|
Joo Jae-Sang
Choi Chan
Jung Seung-Il
Park Kwang-Sung
Kang Taek-Won
Kwon Dong-Deuk
Ryu Soo-Bang
Kim Jun-Seok
|
|
|
Abstract
|
|
|
Purpose:There are many prognostic indicators of bladder tumors including clinical, pathological and molecular markers based on tumor-related factors. This study was performed to evaluate the significance of an elevated level of serum creatinine for predicting progression and recurrence of superficial bladder tumors.
Materials and Methods:One hundred forty-seven patients that initially presented with a superficial bladder tumor(pTa or pT1) except for a carcinoma in situ were retrospectively analyzed according to several factors such as tumor stage, grade, size, multiplicity and serum creatinine for tumor recurrence and progression after a primary transurethral resection.
Results:The elevated serum creatinine group consisted of 20 patients 11 patients experienced recurrence(55.0%) and 3 patients experienced progression(15.0%). The control group consisted of 127 patients 39 patients experienced recurrence(30.7%) and 13 patients experienced progression (10.2%). The presence of an elevated level of serum creatinine and tumor multiplicity were statistically significant prognostic factors for tumor recurrence.
Conclusions:These results can be helpful for predicting the prognosis of transitional cell carcinoma of the bladder and for planning therapeutic and follow-up strategies. (Korean J Urol 2007;48:927-932)
|
|
|
KEYWORD
|
|
|
Urinary bladder neoplasms, Prognosis, Creatinine
|
|
|
FullTexts / Linksout information
|
|
  
|
|
|
Listed journal information
|
|
  
|